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Predicting BRCA1 and BRCA2 gene mutation carriers: comparison of LAMBDA, BRCAPRO, Myriad II, and modified Couch models
CONTEXT: Models have been developed to predict the probability that a person carries a detectable germline mutation in the BRCA1 or BRCA2 genes. Their relative performance in a clinical setting is unclear. OBJECTIVE: To compare the performance characteristics of four BRCA1/BRCA2 gene mutation predic...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933048/ https://ncbi.nlm.nih.gov/pubmed/17636425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-007-9150-z |
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