Log odds of carrying an Ancestral Mutation in BRCA1 or BRCA2 for a Defined personal and family history in an Ashkenazi Jewish woman (LAMBDA)

INTRODUCTION: Ancestral mutations in BRCA1 and BRCA2 are common in people of Ashkenazi Jewish descent and are associated with a substantially increased risk of breast and ovarian cancer. Women considering mutation testing usually have several personal and family cancer characteristics, so predicting...

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Hauptverfasser: Apicella, Carmel, Andrews, Lesley, Hodgson, Shirley V, Fisher, Sheila A, Lewis, Cathryn M, Solomon, Ellen, Tucker, Katherine, Friedlander, Michael, Bankier, Agnes, Southey, Melissa C, Venter, Deon J, Hopper, John L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2003
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC314405/
https://ncbi.nlm.nih.gov/pubmed/14580256
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