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Predicting BRCA1 and BRCA2 gene mutation carriers: comparison of PENN II model to previous study

A number of models have been developed to predict the probability that a person carries a detectable germline mutation in the BRCA1 or BRCA2 genes. Their relative performance in a clinical setting is variable. To compare the performance characteristics of a web-based BRCA1/BRCA2 gene mutation predic...

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Main Authors: Lindor, Noralane M., Johnson, Kiley J., Harvey, Hayden, Pankratz, V. Shane, Domchek, Susan M., Hunt, Katherine, Wilson, Marcia, Smith, M. Cathie, Couch, Fergus
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981620/
https://ncbi.nlm.nih.gov/pubmed/20512419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-010-9348-3
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