Wordt geladen...

High-resolution MAS NMR analysis of PI3-SH3 amyloid fibrils: Backbone conformation and implications for protofilament assembly and structure

The SH3 domain of the PI3 kinase (PI3-SH3 or PI3K-SH3) readily aggregates into fibrils in vitro and has served as an important model system to investigate the molecular properties and mechanism of formation of amyloid fibrils. We describe the molecular conformation of PI3-SH3 in amyloid fibril form...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Bayro, Marvin J., Maly, Thorsten, Birkett, Neil R., MacPhee, Cait E., Dobson, Christopher M., Griffin, Robert G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932965/
https://ncbi.nlm.nih.gov/pubmed/20707313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100864t
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!