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Synergistic Inflammation Is Induced by Blood Degradation Products with Microbial Toll-Like Receptor Agonists and Is Blocked by Hemopexin

Detection of microbial components by immune cells via Toll-like receptors (TLRs) with subsequent induction of inflammation is essential for host defense. However, an overactive immune response can cause tissue damage and sepsis. The endogenous molecule hemoglobin and its derivative heme are often re...

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Detalhes bibliográficos
Main Authors: Lin, Tian, Kwak, Young Ho, Sammy, Fatima, He, Ping, Thundivalappil, Sujatha, Sun, Guangjie, Chao, Wei, Warren, H. Shaw
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932749/
https://ncbi.nlm.nih.gov/pubmed/20617898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/654929
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