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Synergistic Inflammation Is Induced by Blood Degradation Products with Microbial Toll-Like Receptor Agonists and Is Blocked by Hemopexin

Detection of microbial components by immune cells via Toll-like receptors (TLRs) with subsequent induction of inflammation is essential for host defense. However, an overactive immune response can cause tissue damage and sepsis. The endogenous molecule hemoglobin and its derivative heme are often re...

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Autors principals: Lin, Tian, Kwak, Young Ho, Sammy, Fatima, He, Ping, Thundivalappil, Sujatha, Sun, Guangjie, Chao, Wei, Warren, H. Shaw
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932749/
https://ncbi.nlm.nih.gov/pubmed/20617898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/654929
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