Hydrophobic Core Formation and Dehydration in Protein Folding Studied by Generalized-Ensemble Simulations

Despite its small size, chicken villin headpiece subdomain HP36 folds into the native structure with a stable hydrophobic core within several microseconds. How such a small protein keeps up its conformational stability and fast folding in solution is an important issue for understanding molecular me...

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Hlavní autoři: Yoda, Takao, Sugita, Yuji, Okamoto, Yuko
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
Protein
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931739/
https://ncbi.nlm.nih.gov/pubmed/20816077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.045
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