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Hydrophobic Core Formation and Dehydration in Protein Folding Studied by Generalized-Ensemble Simulations
Despite its small size, chicken villin headpiece subdomain HP36 folds into the native structure with a stable hydrophobic core within several microseconds. How such a small protein keeps up its conformational stability and fast folding in solution is an important issue for understanding molecular me...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931739/ https://ncbi.nlm.nih.gov/pubmed/20816077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.045 |
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