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Side chain burial and hydrophobic core packing in protein folding transition states
A critical step in the folding pathway of globular proteins is the formation of a tightly packed hydrophobic core. Several mutational studies have addressed the question of whether tight packing interactions are present during the rate-limiting step of folding. In some of these investigations, subst...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2271162/ https://ncbi.nlm.nih.gov/pubmed/18305200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073105408 |
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