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Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction
Understanding the mechanism of protein folding requires a detailed knowledge of the structural properties of the barriers separating unfolded from native conformations. The S-peptide from ribonuclease S forms its α-helical structure only upon binding to the folded S-protein. We characterized the tra...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3054012/ https://ncbi.nlm.nih.gov/pubmed/21325613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012668108 |
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