Control of Ca(2+) Release by Action Potential Configuration in Normal and Failing Murine Cardiomyocytes

Cardiomyocytes from failing hearts exhibit spatially nonuniform or dyssynchronous sarcoplasmic reticulum (SR) Ca(2+) release. We investigated the contribution of action potential (AP) prolongation in mice with congestive heart failure (CHF) after myocardial infarction. AP recordings from CHF and con...

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Hlavní autoři: Louch, William E., Hake, Johan, Jølle, Guro Five, Mørk, Halvor K., Sjaastad, Ivar, Lines, Glenn T., Sejersted, Ole M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
Cellular Biophysics and Electrophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931738/
https://ncbi.nlm.nih.gov/pubmed/20816049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.055
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