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T-tubule disorganization and reduced synchrony of Ca(2+) release in murine cardiomyocytes following myocardial infarction

In cardiac myocytes, initiation of excitation–contraction coupling is highly localized near the T-tubule network. Myocytes with a dense T-tubule network exhibit rapid and homogeneous sarcoplasmic reticulum (SR) Ca(2+) release throughout the cell. We examined whether progressive changes in T-tubule o...

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Detalhes bibliográficos
Main Authors: Louch, William E, Mørk, Halvor K, Sexton, Joseph, Strømme, Tævje A, Laake, Petter, Sjaastad, Ivar, Sejersted, Ole M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817777/
https://ncbi.nlm.nih.gov/pubmed/16709642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.107227
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