Enhanced Immunogenicity of Stabilized Trimeric Soluble Influenza Hemagglutinin

BACKGROUND: The recent swine-origin H1N1 pandemic illustrates the need to develop improved procedures for rapid production of influenza vaccines. One alternative to the current egg-based manufacture of influenza vaccine is to produce a hemagglutinin (HA) subunit vaccine using a recombinant expressio...

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Autores principales: Weldon, William C., Wang, Bao-Zhong, Martin, Maria P., Koutsonanos, Dimitrios G., Skountzou, Ioanna, Compans, Richard W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931692/
https://ncbi.nlm.nih.gov/pubmed/20824188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012466
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