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L-Valine Ester of Cyclopropavir - a New Antiviral Prodrug

The L-Valine ester of antiviral agent cyclopropavir, valcyclopropavir (6), was synthesized and evaluated for antiviral properties. Prodrug (6) inhibited replication of HCMV virus (Towne and AD169 strain) in HFF cells to approximately the same extent as the parent drug cyclopropavir (5). Stability of...

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Detalhes bibliográficos
Main Authors: Wu, Zhimeng, Drach, John C., Prichard, Mark N., Yanachkova, Milka, Yanachkov, Ivan, Bowlin, Terry L., Zemlicka, Jiri
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931272/
https://ncbi.nlm.nih.gov/pubmed/19794230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP782
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