Загрузка...
Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model
Hydroxyurea has proven clinical efficacy in patients with sickle cell disease. Potential mechanisms for the beneficial effects include fetal hemoglobin induction and the reduction of cell adhesive properties, inflammation and hypercoagulability. Using a murine model of sickle cell disease in which f...
Сохранить в:
| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Ferrata Storti Foundation
2010
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930964/ https://ncbi.nlm.nih.gov/pubmed/20378564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.023325 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|