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Selection, Preparation, and Evaluation of Small-Molecule Inhibitors of Toll-Like Receptor 4
[Image: see text] Toll-like receptor 4 (TLR4), a membrane-spanning receptor protein that functions in complex with its accessory protein MD-2, is an intriguing target for therapeutic development. Herein, we report the identification of a series of novel TLR4 inhibitors and the development of a robus...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical Society
2010
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930797/ https://ncbi.nlm.nih.gov/pubmed/20824192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100041f |
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