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Targeting Toll-like Receptors with Small Molecule Agents

Toll-like receptors (TLRs) are type I transmembrane proteins that are key regulators of both innate and adaptive immune responses. To protect the host from viral and bacterial threats, TLRs trigger a pro-inflammatory immune response by detecting pathogen and danger associated molecular patterns. Con...

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Autors principals: Wang, Xiaohui, Smith, Christina, Yin, Hang
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665707/
https://ncbi.nlm.nih.gov/pubmed/23503527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cs60039d
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