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Structure and Mutagenesis of Neural Cell Adhesion Molecule Domains: EVIDENCE FOR FLEXIBILITY IN THE PLACEMENT OF POLYSIALIC ACID ATTACHMENT SITES
The addition of α2,8-polysialic acid to the N-glycans of the neural cell adhesion molecule, NCAM, is critical for brain development and plays roles in synaptic plasticity, learning and memory, neuronal regeneration, and the growth and invasiveness of cancer cells. Our previous work indicates that th...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930734/ https://ncbi.nlm.nih.gov/pubmed/20573953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.140038 |
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