Sialidase NEU4 Hydrolyzes Polysialic Acids of Neural Cell Adhesion Molecules and Negatively Regulates Neurite Formation by Hippocampal Neurons

Modulation of levels of polysialic acid (polySia), a sialic acid polymer, predominantly associated with the neural cell adhesion molecule (NCAM), influences neural functions, including synaptic plasticity, neurite growth, and cell migration. Biosynthesis of polySia depends on two polysialyltransfera...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Takahashi, Kohta, Mitoma, Junya, Hosono, Masahiro, Shiozaki, Kazuhiro, Sato, Chihiro, Yamaguchi, Kazunori, Kitajima, Ken, Higashi, Hideyoshi, Nitta, Kazuo, Shima, Hiroshi, Miyagi, Taeko
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2012
Θέματα:
Glycobiology and Extracellular Matrices
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340223/
https://ncbi.nlm.nih.gov/pubmed/22393058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.324186
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