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Potentiation of Epidermal Growth Factor-Mediated Oncogenic Transformation by Sialidase NEU3 Leading to Src Activation

We previously demonstrated that sialidase NEU3, a key glycosidase for ganglioside degradation, is up-regulated in various human cancers, leading to increased cell invasion, motility and survival of cancer cells possibly through activation of EGF signaling. Its up-regulation is also important for pro...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yamamoto, Koji, Takahashi, Kohta, Shiozaki, Kazuhiro, Yamaguchi, Kazunori, Moriya, Setsuko, Hosono, Masahiro, Shima, Hiroshi, Miyagi, Taeko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372364/
https://ncbi.nlm.nih.gov/pubmed/25803810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120578
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