Role of Glutaredoxin1 and Glutathione in Regulating the Activity of the Copper-transporting P-type ATPases, ATP7A and ATP7B

The copper-transporting P-type ATPases (Cu-ATPases), ATP7A and ATP7B, are essential for the regulation of intracellular copper homeostasis. In this report we describe new roles for glutathione (GSH) and glutaredoxin1 (GRX1) in Cu homeostasis through their regulation of Cu-ATPase activity. GRX1 is a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Singleton, William C. J., McInnes, Kelly T., Cater, Michael A., Winnall, Wendy R., McKirdy, Ross, Yu, Yu, Taylor, Philip E., Ke, Bi-Xia, Richardson, Des R., Mercer, Julian F. B., La Fontaine, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930710/
https://ncbi.nlm.nih.gov/pubmed/20566629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.154468
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados