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Clusterin and COMMD1 Independently Regulate Degradation of the Mammalian Copper ATPases ATP7A and ATP7B

ATP7A and ATP7B are copper-transporting P(1B)-type ATPases (Cu-ATPases) that are critical for regulating intracellular copper homeostasis. Mutations in the genes encoding ATP7A and ATP7B lead to copper deficiency and copper toxicity disorders, Menkes and Wilson diseases, respectively. Clusterin and...

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Detalhes bibliográficos
Main Authors: Materia, Stephanie, Cater, Michael A., Klomp, Leo W. J., Mercer, Julian F. B., La Fontaine, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268409/
https://ncbi.nlm.nih.gov/pubmed/22130675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.302216
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