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Clusterin (Apolipoprotein J), a Molecular Chaperone That Facilitates Degradation of the Copper-ATPases ATP7A and ATP7B

The copper-transporting P(1B)-type ATPases (Cu-ATPases) ATP7A and ATP7B are key regulators of physiological copper levels. They function to maintain intracellular copper homeostasis by delivering copper to secretory compartments and by trafficking toward the cell periphery to export excess copper. M...

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Auteurs principaux: Materia, Stephanie, Cater, Michael A., Klomp, Leo W. J., Mercer, Julian F. B., La Fontaine, Sharon
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060459/
https://ncbi.nlm.nih.gov/pubmed/21242307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190546
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