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Clusterin and COMMD1 Independently Regulate Degradation of the Mammalian Copper ATPases ATP7A and ATP7B

ATP7A and ATP7B are copper-transporting P(1B)-type ATPases (Cu-ATPases) that are critical for regulating intracellular copper homeostasis. Mutations in the genes encoding ATP7A and ATP7B lead to copper deficiency and copper toxicity disorders, Menkes and Wilson diseases, respectively. Clusterin and...

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Main Authors: Materia, Stephanie, Cater, Michael A., Klomp, Leo W. J., Mercer, Julian F. B., La Fontaine, Sharon
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268409/
https://ncbi.nlm.nih.gov/pubmed/22130675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.302216
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