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Human glutaredoxin-1 can transfer copper to isolated metal binding domains of the P(1B)-type ATPase, ATP7B

Intracellular copper (Cu) in eukaryotic organisms is regulated by homeostatic systems, which rely on the activities of soluble metallochaperones that participate in Cu exchange through highly tuned protein-protein interactions. Recently, the human enzyme glutaredoxin-1 (hGrx1) has been shown to poss...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maghool, Shadi, Fontaine, Sharon La, Roberts, Blaine R., Kwan, Ann H., Maher, Megan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057996/
https://ncbi.nlm.nih.gov/pubmed/32139726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60953-z
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