Mitotic Down-regulation of p190RhoGAP Is Required for the Successful Completion of Cytokinesis

p190RhoGAP-A (p190) is a GTPase-activating protein known to regulate actin cytoskeleton dynamics by decreasing RhoGTP levels through activation of Rho intrinsic GTPase activity. We have previously shown that p190 protein levels are cell cycle-regulated, decreasing in mitosis, and that this decrease...

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Main Authors: Manchinelly, Sergio A. Sánchez, Miller, Joyce Agati, Su, Ling, Miyake, Tsuyoshi, Palmer, Lisa, Mikawa, Masahito, Parsons, Sarah J.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930692/
https://ncbi.nlm.nih.gov/pubmed/20534586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.103804
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