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Allogeneic T cells impair engraftment and hematopoiesis after stem cell transplantation

Because of the perception that depleting hematopoietic grafts of T cells will result in poorer immune recovery and in increased risk of graft rejection, pure hematopoietic stem cells (HSC), which avoid the potentially lethal complication of graft-versus-host disease (GVHD), have not been used for al...

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Main Authors: Müller, Antonia M. S., Linderman, Jessica A., Florek, Mareike, Miklos, David, Shizuru, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930440/
https://ncbi.nlm.nih.gov/pubmed/20679222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009220107
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