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Huntingtin as an Essential Integrator of Intracellular Vesicular Trafficking

The neurodegenerative disorder Huntington’s Disease is caused by an expansion in the polyglutamine repeat region of the protein huntingtin. Multiple studies in cellular and animal model systems indicate that this mutation imparts a novel toxic function required for disease pathogenesis. However, hun...

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Bibliografski detalji
Glavni autori: Caviston, Juliane P., Holzbaur, Erika L. F.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930405/
https://ncbi.nlm.nih.gov/pubmed/19269181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2009.01.005
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