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Huntingtin as an Essential Integrator of Intracellular Vesicular Trafficking
The neurodegenerative disorder Huntington’s Disease is caused by an expansion in the polyglutamine repeat region of the protein huntingtin. Multiple studies in cellular and animal model systems indicate that this mutation imparts a novel toxic function required for disease pathogenesis. However, hun...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930405/ https://ncbi.nlm.nih.gov/pubmed/19269181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2009.01.005 |
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