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Development of cell cultures that express hepatitis B virus to high levels and accumulate cccDNA
Establishment of an infection with hepatitis B virus (HBV) requires synthesis and maintenance of a covalently closed circular DNA (cccDNA) form of the viral genome in the nucleus of host cells. To facilitate investigation of the synthesis of cccDNA, cell cultures were developed that express HBV to h...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930070/ https://ncbi.nlm.nih.gov/pubmed/20600328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2010.06.015 |
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