Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus.

Hepatitis B virus (HBV) is one of the major etiological pathogens for liver cirrhosis and hepatocellular carcinoma. Chronic HBV infection is a key factor in these severe liver diseases. During infection, HBV forms a nuclear viral episome in the form of covalently closed circular DNA (cccDNA). Curren...

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Bibliografske podrobnosti
Main Authors: Kouichi Kitamura, Lusheng Que, Miyuki Shimadu, Miki Koura, Yuuki Ishihara, Kousho Wakae, Takashi Nakamura, Koichi Watashi, Takaji Wakita, Masamichi Muramatsu
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2018-06-01
Serija:PLoS Pathogens
Online dostop:http://europepmc.org/articles/PMC6013022?pdf=render
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