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Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus.
Hepatitis B virus (HBV) is one of the major etiological pathogens for liver cirrhosis and hepatocellular carcinoma. Chronic HBV infection is a key factor in these severe liver diseases. During infection, HBV forms a nuclear viral episome in the form of covalently closed circular DNA (cccDNA). Curren...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2018-06-01
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| Series: | PLoS Pathogens |
| Acceso en liña: | http://europepmc.org/articles/PMC6013022?pdf=render |
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