TGF-β Suppression of HBV RNA through AID-Dependent Recruitment of an RNA Exosome Complex

Transforming growth factor (TGF)-β inhibits hepatitis B virus (HBV) replication although the intracellular effectors involved are not determined. Here, we report that reduction of HBV transcripts by TGF-β is dependent on AID expression, which significantly decreases both HBV transcripts and viral DN...

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Udgivet i:PLoS Pathog
Main Authors: Liang, Guoxin, Liu, Guangyan, Kitamura, Kouichi, Wang, Zhe, Chowdhury, Sajeda, Monjurul, Ahasan Md, Wakae, Kousho, Koura, Miki, Shimadu, Miyuki, Kinoshita, Kazuo, Muramatsu, Masamichi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383551/
https://ncbi.nlm.nih.gov/pubmed/25836330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004780
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