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CD39/ENTPD1 expression by CD4(+)Foxp3(+) regulatory T cells promotes hepatic metastatic tumor growth in mice
BACKGROUND & AIMS: Adenosine mediates immune suppression and is generated by the ectonucleotidases CD39 (ENTPD1) and CD73 that are expressed on vascular endothelial cells and regulatory T cells (Treg). Although tumor-infiltrating immune cells include Foxp3(+) Treg, it is not clear whether local...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930043/ https://ncbi.nlm.nih.gov/pubmed/20546740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.05.007 |
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