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Stretch-Induced Stress Fiber Remodeling and the Activations of JNK and ERK Depend on Mechanical Strain Rate, but Not FAK

BACKGROUND: Cells within tissues are subjected to mechanical forces caused by extracellular matrix deformation. Cells sense and dynamically respond to stretching of the matrix by reorienting their actin stress fibers and by activating intracellular signaling proteins, including focal adhesion kinase...

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Detalhes bibliográficos
Main Authors: Hsu, Hui-Ju, Lee, Chin-Fu, Locke, Andrea, Vanderzyl, Susan Q., Kaunas, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930005/
https://ncbi.nlm.nih.gov/pubmed/20814573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012470
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