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Stretch-Induced Stress Fiber Remodeling and the Activations of JNK and ERK Depend on Mechanical Strain Rate, but Not FAK

BACKGROUND: Cells within tissues are subjected to mechanical forces caused by extracellular matrix deformation. Cells sense and dynamically respond to stretching of the matrix by reorienting their actin stress fibers and by activating intracellular signaling proteins, including focal adhesion kinase...

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Autori principali: Hsu, Hui-Ju, Lee, Chin-Fu, Locke, Andrea, Vanderzyl, Susan Q., Kaunas, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930005/
https://ncbi.nlm.nih.gov/pubmed/20814573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012470
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