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Cooperative effects of Rho and mechanical stretch on stress fiber organization

The small GTPase Rho regulates the formation of actin stress fibers in adherent cells through activation of its effector proteins Rho-kinase and mDia. We found in bovine aortic endothelial cells that inhibitions of Rho, Rho-kinase, and mDia (with C3, Y27632, and F1F2Δ1, respectively) suppressed stre...

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Main Authors: Kaunas, Roland, Nguyen, Phu, Usami, Shunichi, Chien, Shu
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276069/
https://ncbi.nlm.nih.gov/pubmed/16247009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506041102
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