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Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry
To study the roles of anisotropic cell morphology and directionality of mechanical force in apoptosis, the spreading of human umbilical vein endothelial cells (HUVECs) was constrained by growing on micropatterned (MP) strips of fibronectin (FN, 20 μg/cm(2)) with widths of 15, 30, and 60 μm on silico...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783086/ https://ncbi.nlm.nih.gov/pubmed/17229844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609806104 |
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