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FAK Is Required for TGFβ-induced JNK Phosphorylation in Fibroblasts: Implications for Acquisition of a Matrix-remodeling Phenotype

Transforming growth factor β (TGFβ) plays a critical role in connective tissue remodeling by fibroblasts during development, tissue repair, and fibrosis. We investigated the molecular pathways in the transmission of TGFβ signals that lead to features of connective tissue remodeling, namely formation...

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Detalhes bibliográficos
Main Authors: Liu, Shangxi, Shi-wen, Xu, Kennedy, Laura, Pala, Daphne, Chen, Yunliang, Eastwood, Mark, Carter, David E., Black, Carol M., Abraham, David J., Leask, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877111/
https://ncbi.nlm.nih.gov/pubmed/17409352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-12-1121
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