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Abnormal Expression of the GIRK2 Potassium Channel in Hippocampus, Frontal Cortex and Substantia Nigra of Ts65Dn Mouse: A Model of Down Syndrome

Ts65Dn, a mouse model of Down syndrome (DS), demonstrates abnormal hippocampal synaptic plasticity and behavioral abnormalities related to spatial learning and memory. The molecular mechanisms leading to these impairments have not been identified. In this study, we focused on the G-protein-activated...

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Hlavní autoři: Harashima, Chie, Jacobowitz, David M., Witta, Jassir, Borke, Rosemary C., Best, Tyler K., Siarey, Richard J., Galdzicki, Zygmunt
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929960/
https://ncbi.nlm.nih.gov/pubmed/16374808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.20844
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