Longitudinal Characterization of Brain Atrophy of a Huntington Disease Mouse Model by Automated Morphological Analyses of Magnetic Resonance Images

Mouse models of human diseases play crucial roles in understanding disease mechanisms and developing therapeutic measures. Huntington’s disease (HD) is characterized by striatal atrophy that begins long before the onset of motor symptoms. In symptomatic HD, striatal volumes decline predictably with...

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Detalhes bibliográficos
Main Authors: Zhang, Jiangyang, Peng, Qi, Li, Qing, Jahanshad, Neda, Hou, Zhipeng, Jiang, Mali, Masuda, Naoki, Langbehn, Douglas R., Miller, Michael I., Mori, Susumu, Ross, Christopher A., Duan, Wenzhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929697/
https://ncbi.nlm.nih.gov/pubmed/19850133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2009.10.027
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