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Acetaminophen-Associated Hepatic Injury: Evaluation of Acetaminophen Protein Adducts in Children and Adolescents With Acetaminophen Overdose

Acetaminophen protein adducts (APAP adducts) were quantified in 157 adolescents and children presenting at eight pediatric hospitals with the chief complaint of APAP overdose. Two of the patients required liver transplantation, whereas all the others recovered spontaneously. Peak APAP adducts correl...

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Autores principales: James, LP, Capparelli, EV, Simpson, PM, Letzig, L, Roberts, D, Hinson, JA, Kearns, GL, Blumer, JL, Sullivan, JE
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929246/
https://ncbi.nlm.nih.gov/pubmed/18923390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2008.190
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