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Mutations in the Antifolate-Resistance-Associated Genes Dihydrofolate Reductase and Dihydropteroate Synthase in Plasmodium vivax Isolates from Malaria-Endemic Countries

Parasite dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) are known target enzymes of antifolate drugs used for the treatment and prophylaxis of persons with malaria. We sequenced the Plasmodium vivax dihydrofolate reductase (pvdhfr) and dihydropteroate synthase (pvdhps) genes to e...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lu, Feng, Lim, Chae Seung, Nam, Deok Hwa, Kim, Kwonkee, Lin, Khin, Kim, Tong-Soo, Lee, Hyeong-Woo, Chen, Jun-Hu, Wang, Yue, Sattabongkot, Jetsumon, Han, Eun-Taek
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society of Tropical Medicine and Hygiene 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929037/
https://ncbi.nlm.nih.gov/pubmed/20810806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2010.10-0004
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