Angiotensin-Converting Enzyme N-Terminal Inactivation Alleviates Bleomycin-Induced Lung Injury

Bleomycin has potent anti-oncogenic properties for several neoplasms, but drug administration is limited by bleomycin-induced lung fibrosis. Inhibition of the renin-angiotensin system has been suggested to decrease bleomycin toxicity, but the efficacy of such strategies remains uncertain and somewha...

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Bibliographic Details
Main Authors: Li, Ping, Xiao, Hong D., Xu, Jianguo, Ong, Frank S., Kwon, Mike, Roman, Jesse, Gal, Anthony, Bernstein, Kenneth E., Fuchs, Sebastien
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928946/
https://ncbi.nlm.nih.gov/pubmed/20651228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.081127
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