Mice with Enhanced Macrophage Angiotensin-Converting Enzyme Are Resistant to Melanoma

Angiotensin-converting enzyme (ACE) is a peptidase responsible for the cleavage of angiotensin I and several other peptides. Here, gene targeting was used to switch control of the ACE locus from the endogenous promoter to the macrophage-specific c-fms promoter. Challenge of these mice, called ACE 10...

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Detalhes bibliográficos
Main Authors: Shen, Xiao Z., Li, Ping, Weiss, Daiana, Fuchs, Sebastien, Xiao, Hong D., Adams, Jon A., Williams, Ifor R., Capecchi, Mario R., Taylor, W. Robert, Bernstein, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899454/
https://ncbi.nlm.nih.gov/pubmed/17525278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061205
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