Angiotensin-converting enzyme is required for normal myelopoiesis

Inhibition of angiotensin-converting enzyme (ACE) induces anemia in humans and mice, but it is unclear whether ACE is involved in other aspects of hematopoiesis. Here, we systemically evaluated ACE-knockout (KO) mice and found myelopoietic abnormalities characterized by increased bone marrow myelobl...

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Detalhes bibliográficos
Main Authors: Lin, Chentao, Datta, Vivekanand, Okwan-Duodu, Derick, Chen, Xu, Fuchs, Sebastien, Alsabeh, Randa, Billet, Sandrine, Bernstein, Kenneth E., Shen, Xiao Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058713/
https://ncbi.nlm.nih.gov/pubmed/21148418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-169433
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