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Intrarenal Angiotensin-Converting Enzyme Induces Hypertension in Response to Angiotensin I Infusion
The contribution of the intrarenal renin-angiotensin system to the development of hypertension is incompletely understood. Here, we used targeted homologous recombination to generate mice that express angiotensin-converting enzyme (ACE) in the kidney tubules but not in other tissues. Mice homozygous...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Nephrology
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060439/ https://ncbi.nlm.nih.gov/pubmed/21115616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010060624 |
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