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The carboxypeptidase angiotensin converting enzyme (ACE) shapes the MHC class I peptide repertoire
The surface presentation of peptides by major histocompatibility complex (MHC) class I molecules is critical to CD8(+) T cell mediated adaptive immune responses. Aminopeptidases are implicated in the editing of peptides for MHC class I loading, but C-terminal editing is thought due to proteasome cle...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197883/ https://ncbi.nlm.nih.gov/pubmed/21964607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2107 |
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