Resveratrol Inhibits Renal Fibrosis in the Obstructed Kidney : Potential Role in Deacetylation of Smad3

Transforming growth factor-β1 (TGF-β1) promotes tissue fibrosis through the Smad3 signaling pathway. While phosphorylation is known to regulate Smad3 function, recent in vitro studies have suggested that acetylation may also regulate Smad3 function. This study investigated Smad3 acetylation in renal...

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Hlavní autoři: Li, Jinhua, Qu, Xinli, Ricardo, Sharon D., Bertram, John F., Nikolic-Paterson, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Short Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928940/
https://ncbi.nlm.nih.gov/pubmed/20651248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090923
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