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Endothelial-Myofibroblast Transition Contributes to the Early Development of Diabetic Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice

Diabetic nephropathy is the leading cause of chronic renal failure. Myofibroblasts play a major role in the synthesis and secretion of extracellular matrix in diabetic renal fibrosis. Increasing evidence suggests that endothelial cells may undergo endothelial-myofibroblast transition under physiolog...

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Détails bibliographiques
Auteurs principaux: Li, Jinhua, Qu, Xinli, Bertram, John F.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751535/
https://ncbi.nlm.nih.gov/pubmed/19729486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090096
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