Resveratrol Inhibits Renal Fibrosis in the Obstructed Kidney : Potential Role in Deacetylation of Smad3

Transforming growth factor-β1 (TGF-β1) promotes tissue fibrosis through the Smad3 signaling pathway. While phosphorylation is known to regulate Smad3 function, recent in vitro studies have suggested that acetylation may also regulate Smad3 function. This study investigated Smad3 acetylation in renal...

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Detalhes bibliográficos
Main Authors: Li, Jinhua, Qu, Xinli, Ricardo, Sharon D., Bertram, John F., Nikolic-Paterson, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928940/
https://ncbi.nlm.nih.gov/pubmed/20651248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090923
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