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NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53
A cohort of genes associated with embryonic stem (ES) cell behaviour, including NANOG, are expressed in a number of human cancers. They form an ES-like signature we first described in glioblastoma multiforme (GBM), a highly invasive and incurable brain tumour. We have also shown that HEDGEHOG-GLI (H...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928692/ https://ncbi.nlm.nih.gov/pubmed/20581802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.137 |
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